What you need to know
COVID-19 vaccines are safe and effective. Millions of people in the United States have received COVID-19 vaccines, and these vaccines will undergo the most intensive safety monitoring in U.S. history.
The CDC recommends you get a COVID-19 vaccine as soon as you are eligible. Adverse events described on this page have been reported to the Vaccine Adverse Event Reporting System (VAERS)external icon. VAERS accepts reports of any adverse event following vaccination, even if it is not clear the vaccine caused the problem. CDC, FDA, and other federal partners will continue to monitor the safety of the COVID-19 vaccines.
Anaphylaxis after COVID-19 vaccination
Anaphylaxis after COVID-19 vaccination is rare. If this occurs, vaccination providers can effectively and immediately treat the reaction.
CDC and FDA scientists have evaluated reports from people who experienced a type of severe allergic reaction—anaphylaxis—after getting a COVID-19 vaccine. Anaphylaxis after COVID-19 vaccination is rare and occurred in approximately 2 to 5 people per million vaccinated in the United States based on events reported to VAERS. This kind of allergic reaction almost always occurs within 30 minutes after vaccination. Fortunately, vaccination providers have medicines available to effectively and immediately treat patients who experience anaphylaxis following vaccination. Learn more about COVID-19 vaccines and allergic reactions.
Reports of death after COVID-19 vaccination
Over 145 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through March 29, 2021. During this time, VAERS received 2,509 reports of death (0.0017%) among people who received a COVID-19 vaccine. CDC and FDA physicians review each case report of death as soon as notified and CDC requests medical records to further assess reports. A review of available clinical information including death certificates, autopsy, and medical records revealed no evidence that vaccination contributed to patient deaths. CDC and FDA will continue to investigate reports of adverse events, including deaths, reported to VAERS.
Have you experienced a side effect following COVID-19 vaccination?
You can report it to VAERS.